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th.webster@northeastern.edu

Faculty Profile

Thomas Webster

Professor and Department Chair, Chemical Engineering
Art Zafiropoulo Chair in Engineering
Affiliated Faculty, Bioengineering
617.373.2989
313 Snell Engineering Center
360 Huntington Avenue
Boston, MA 02115

Biography

Joined the Chemical Engineering Department in Fall 2012.

The primary focus of our research is the design, synthesis, and evaluation of nanomaterials for various medical applications. This includes self-assembled chemistries, nanoparticles, nanotubes, and nanostructured surfaces. Medical applications include inhibiting bacteria growth, inflammation, and promoting tissue growth. Tissues of particular interest are bone, cartilage, skin, nervous system, bladder, cardiovascular, and vascular. There is also an interest in anti-cancer applications where nanomaterials can be used to decrease cancer cell functions without the use of pharmaceutical agents. There is also a large interest in developing in situ sensors which can sense biological responses to medical devices and respond in real time to ensure implant success. Lastly, there is an interest in understanding the environmental and human health toxicity of nanomaterials.

Education

  • B.S. (Chemical Engineering) University of Pittsburgh, 1995
  • Ph.D. (Biomedical Engineering) Rensselaer Polytechnic Institute, 2000

Research & Scholarship Interests

design, synthesis, and evaluation of nanomaterials for various medical applications, including self-assembled chemistries, nanoparticles, nanotubes, and nanostructured surfaces
Affiliated With

Department Research Areas

College Research Initiatives

Honors & Awards

  • Fellow, American Institute for Medical and Biological Engineers
  • Fellow, American Society for Nanomedicine
  • Fellow, Biomaterials Science and Engineering
  • Fellow, Biomedical Engineering Society
  • Fellow, Ernst Strungmann Foundation
  • Fellow, International College of Fellows - Biomaterials Science and Engineering

Selected Publications

  • M. Zile, S. Puckett, and T.J. Webster, “Nanostructured titanium promotes keratinocyte density,” Journal of Biomedical Materials Research Part A, 97A(1): 59-65 (2011).
  • D. Gorth, D. Rand, T.J. Webster, “Silver nanoparticle toxicity in Drosophila: Size does matter”, International Journal of Nanomedicine, 6:343-350 (2011).
  • M. Machado, D. Cheng, K. Tarquinio, and T.J. Webster, “Nanotechnology: Pediatric applications,” Pediatric Research, 67(5):500-504 (2010).
  • S. Puckett, E. Taylor, T. Raimondo, and T.J. Webster, “The relationship between the nanostructure of titanium surfaces and bacterial attachment,” Biomaterials, 31(4): 706-713 (2010).
  • N. Tran and T.J. Webster, “Magnetic nanoparticles: Biomedical applications and challenges,” Journal of Materials Chemistry, 20(40): 8760-8767 (2010).
  • P. Tran, L. Zhang and T.J. Webster, “Carbon nanofibers and carbon nanotubes in regenerative medicine,” Advanced Drug Delivery Reviews, 61(12): 1097-114 (2009).
  • L. Zhang and T. J. Webster, “Nanotechnology and nanomaterials: Promises for improved tissue regeneration,” NanoToday, 4(1): 66-80 (2009).
  • S. Sirivisoot and T.J. Webster, “Multiwalled carbon nanotubes enhance electrochemical properties of titanium to determine in situ bone formation,” Nanotechnology, 19(29): 295101-295113 (2008).
  • J. Lu, M. Rao, N. C. MacDonald, D. Khang, T.J. Webster, “Improved endothelial cell adhesion and proliferation on patterned titanium surfaces with rationally designed, micrometer to nanometer features,” Acta Biomaterialia, 4(1): 192-201 (2008).
  • D. Khang, S.Y. Kim, P. Liu-Synder, G.T.R. Palmore, S.M. Durbin, T.J. Webster, “Enhanced fibronectin adsorption on carbon nanotubes/poly(carbonate) urethane: independent role of surface nano roughness and associated surface energy,” Biomaterials, 28(32):4745-4768 (2007).
  • H. Liu and T.J. Webster, “Nanomedicine for implants: A review of studies and necessary experimental tools,” Biomaterials, 28(2): 354-369 (2007).
  • S. Sirivisoot, C. Yao, X. Xiao, B. W. Sheldon, T.J. Webster, “Greater osteoblast functions on multiwalled carbon nanotubular titanium for orthopedics applications,” Nanotechnology, 18(36):365102-365112 (2007).
  • P. Liu-Synder and T.J. Webster, “Designing drug-delivery systems for the nervous system using nanotechnology: opportunities and challenges,” Expert Review of Medical Devices, 3(6):683-687 (2006).
  • P. Tran, L. Sarin, R. Hurt, T.J. Webster, "Titanium Surfaces with Adherent Selenium Nanoclusters as a Novel Anti-cancer Orthopedic Material", Journal of Biomedical Materials Research, 93(4), 2014, 1417-1428
  • P. Tran, L. Sarin, R. Hurt, T.J. Webster, "Opportunities for Nanotechnology-enabled Bioactive Bone Implants", Journal of Materials Chemistry, 19, 2009, 2653-2659 
  • E.M. Christenson, K. Anseth, T.J. Webster, A.G. Mikos, et al., "Nanobiomaterial applications in orthopaedics", Journal of Orthopaedic Research 25, 2007, 11-22
  • G. Balasundaram, T.J. Webster, "A Perspective on Nanophase Materials for Orthopedic Implant Applications", Journal of Materials Chemistry, 16, 2006, 3737-3745 
  • A. Chun, J. G. Moralez, H. Fenniri, T.J. Webster, "Helical Rosette Nanotubes: A More Effective Orthopaedic Implant Material", Nanotechnology, 15, 2004, 234-239 
  • T.J. Webster, J.U. Ejiofor, "Increased Osteoblast Adhesion on Nanophase Metals", Biomaterials, 25, 2004, 4731-4739
See Google Scholar Profile for all publications »

Related News

August 17, 2017

ChE Professor & Chair Tom Webster will give the keynote talk "Commercializing Nanomedicine: The Future of Biomaterials is Now" at the XXVI International Materials Research Congress.

August 9, 2017

The Summit on Organ Banking through Converging Technologies brought together leading scientists and engineers, as well as other key stakeholders from government, industry, academia, and the nonprofit...

August 2, 2017

ChE Professor & Chair Thomas Webster and PhD students Mian Wang, Gujie Mi, Di Shi, Nicole Bassous and alumnus Daniel Hickey published the review article “Nanotechnology and Nanomaterials for Improving Neural Interfaces” in the journal Advanced Functional Materials.

Related Events

27
Mar

Raytheon Amphitheater, 240 EC

1:30 pm
04
Jun

Webinar

1:00 pm to 2:00 pm
25
Aug

Webinar

12:00 pm to 1:00 pm