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th.webster@neu.edu

Faculty Profile

Thomas Webster

Arthur W. Zafiropoulo Chair & Professor, Chemical Engineering
Affiliated Faculty, Bioengineering
617.373.2989
313 Snell Engineering Center
360 Huntington Avenue
Boston, MA 02115

Biography

The primary focus of our research is the design, synthesis, and evaluation of nanomaterials for various medical applications. This includes self-assembled chemistries, nanoparticles, nanotubes, and nanostructured surfaces. Medical applications include inhibiting bacteria growth, inflammation, and promoting tissue growth. Tissues of particular interest are bone, cartilage, skin, nervous system, bladder, cardiovascular, and vascular. There is also an interest in anti-cancer applications where nanomaterials can be used to decrease cancer cell functions without the use of pharmaceutical agents. There is also a large interest in developing in situ sensors which can sense biological responses to medical devices and respond in real time to ensure implant success. Lastly, there is an interest in understanding the environmental and human health toxicity of nanomaterials.

Education

  • B.S. (Chemical Engineering) University of Pittsburgh, 1995
  • Ph.D. (Biomedical Engineering) Rensselaer Polytechnic Institute, 2000

Research & Scholarship Interests

design, synthesis, and evaluation of nanomaterials for various medical applications, including self-assembled chemistries, nanoparticles, nanotubes, and nanostructured surfaces
Affiliated With

Department Research Areas

College Research Initiatives

Honors & Awards

  • Fellow, American Institute for Medical and Biological Engineers
  • Fellow, American Society for Nanomedicine
  • Fellow, Biomedical Engineering Society
  • Fellow, Ernst Strungmann Foundation

Selected Publications

  • M. Zile, S. Puckett, and T.J. Webster, “Nanostructured titanium promotes keratinocyte density,” Journal of Biomedical Materials Research Part A, 97A(1): 59-65 (2011).
  • D. Gorth, D. Rand, T.J. Webster, “Silver nanoparticle toxicity in Drosophila: Size does matter”, International Journal of Nanomedicine, 6:343-350 (2011).
  • M. Machado, D. Cheng, K. Tarquinio, and T.J. Webster, “Nanotechnology: Pediatric applications,” Pediatric Research, 67(5):500-504 (2010).
  • S. Puckett, E. Taylor, T. Raimondo, and T.J. Webster, “The relationship between the nanostructure of titanium surfaces and bacterial attachment,” Biomaterials, 31(4): 706-713 (2010).
  • N. Tran and T.J. Webster, “Magnetic nanoparticles: Biomedical applications and challenges,” Journal of Materials Chemistry, 20(40): 8760-8767 (2010).
  • P. Tran, L. Zhang and T.J. Webster, “Carbon nanofibers and carbon nanotubes in regenerative medicine,” Advanced Drug Delivery Reviews, 61(12): 1097-114 (2009).
  • L. Zhang and T. J. Webster, “Nanotechnology and nanomaterials: Promises for improved tissue regeneration,” NanoToday, 4(1): 66-80 (2009).
  • S. Sirivisoot and T.J. Webster, “Multiwalled carbon nanotubes enhance electrochemical properties of titanium to determine in situ bone formation,” Nanotechnology, 19(29): 295101-295113 (2008).
  • J. Lu, M. Rao, N. C. MacDonald, D. Khang, T.J. Webster, “Improved endothelial cell adhesion and proliferation on patterned titanium surfaces with rationally designed, micrometer to nanometer features,” Acta Biomaterialia, 4(1): 192-201 (2008).
  • D. Khang, S.Y. Kim, P. Liu-Synder, G.T.R. Palmore, S.M. Durbin, T.J. Webster, “Enhanced fibronectin adsorption on carbon nanotubes/poly(carbonate) urethane: independent role of surface nano roughness and associated surface energy,” Biomaterials, 28(32):4745-4768 (2007).
  • H. Liu and T.J. Webster, “Nanomedicine for implants: A review of studies and necessary experimental tools,” Biomaterials, 28(2): 354-369 (2007).
  • S. Sirivisoot, C. Yao, X. Xiao, B. W. Sheldon, T.J. Webster, “Greater osteoblast functions on multiwalled carbon nanotubular titanium for orthopedics applications,” Nanotechnology, 18(36):365102-365112 (2007).
  • P. Liu-Synder and T.J. Webster, “Designing drug-delivery systems for the nervous system using nanotechnology: opportunities and challenges,” Expert Review of Medical Devices, 3(6):683-687 (2006).

Related News

December 8, 2014

Product Lifecycle Stories recently published an article entitled, " Engineers Join the Battle to Control Ebola ," featuring Professor and Endowed Chair Thomas Webster's research efforts to help detect and cure patients infected with Ebola.

December 8, 2014

New England Cable News (NECN) interviewed Professor and Endowed Chair Thomas Webster regarding the Center for Disease Control's (CDC) claim that flu mutations may result in a less effective vaccine this year.

December 5, 2014

Professor and Endowed Chair Thomas Webster will be giving a plenary lecture entitled, "Transitioning from Nano- to Pico-Technology: Toxicity, Infection, and Tissue Growth," at the International Conference on Translational Medicine (T-NANO 2014) .