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s.murthy@northeastern.edu

Profile

Biography

Joined the Chemical Engineering Department in Fall 2005.

The primary focus of our research is the design of microfluidic devices for applications in clinical diagnostics and regenerative medicine. These devices are fabricated using technology originally designed for the semiconductor industry and are capable of handling and manipulating small volumes of fluids (down to tens of microliters) and small numbers of cells. Our expertise is in functionalizing microfluidic channels with a broad range of biomolecules and achieving high-resolution cell separation with these simple and easy-to-use devices.

Education

  • B.S. (Chemical Engineering) Johns Hopkins University, 1999
  • Ph.D. (Materials Science and Engineering) Massachusetts Institute of Technology, 2003
  • Postdoctoral Fellowship Harvard Medical School and Massachusetts General Hospital, 2003-2005

Research & Scholarship Interests

Microfluidic isolation of stem and progenitor cells, point-of-care diagnostics, cell surface phenomena during microfluidic flow, nanoscale probes for cell stimulation, and biopassive/bioactive coatings for neurological implants
Affiliated With

Department Research Areas

College Research Initiatives

Honors & Awards

  • 2014 COE Faculty Fellow
  • National Science Foundation CAREER Award
  • Søren Buus Outstanding Research Award

Selected Publications

  • A. Kozbial, L. Bhandary, B.B. Collier, C.S. Eickhoff, D.F. Hoft, S.K. Murthy, Automated Generation of Immature Dendritic Cells in a Single Use System, Journal of Immunological Methods 2018, 457, 53-65
  • H. Sallmon, A. Hatch, S.K. Murthy, B.D. Plouffe, G. Hansmann, Circulating Endothelial Cell Quantification by Microfluidics Chip in Pulmonary Arterial Hypertension, American Journal of Respiratory Cell and Molecular Biology 2017, 56, 680-682
  • T. Narahari, D. Dendukuri, and S.K. Murthy, Electrically-Actuated Valves for Woven Fabric Lateral Flow Devices, Analytical Chemistry 2017, 89, 4671-4679
  • D.I. Walsh, D.S. Kong, S.K. Murthy, P.A. Carr, Enabling Microfluidics: From Clean Rooms to Makerspaces,” Trends in Biotechnology 2017, 35, 383-392.
  • B.D. Plouffe and S.K. Murthy, Fluorescence-Based Lateral Flow Assays for Rapid Oral Fluid Roadside Detection of Cannabis Use, Electrophoresis 2017, 38, 501-5016
  • D.I. Walsh, S.K. Murthy, A. Russom, Ultra-High-Throughput Sample Preparation System for Lymphocyte Immunophenotyping Point-of-Care Diagnostics, Journal of Laboratory Automation 2016

Related News

October 17, 2018

Quad Technologies, which was co-founded by ChE Professor Shashi Murthy, Sean Kevlahan (PhD ’13), Adam Hatch (PhD ’14), and Brian Plouffe (PhD ’11), and recently acquired by Bio-Techne, has developed a material, called QuickGel, that can be used to isolate genetically engineered T-cells that would allow a patient's immune system to target the cancer.

June 13, 2018

Bio-Techne will acquire the spinout company Quad Technologies, which was co-founded by ChE Professor Shashi Murthy, Sean Kevlahan (PhD ’13), Adam Hatch (PhD ’14), and Brian Plouffe (PhD ’11).

May 1, 2018

Congratulations to all the winners of the faculty and staff awards, and to everyone for their hard work and dedication during the 2017-2018 academic school year. Faculty Fellow Guohao Dai, BioE...

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