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Faculty Profile

Edgar D. Goluch

Associate Professor, Chemical Engineering
Affiliated Faculty, Bioengineering
Affiliated Faculty, Biology
253 Egan
360 Huntington Avenue
Boston, MA 02115


Joined the Chemical Engineering Department in Fall 2010.

The primary focus of our research is the development of detection strategies that are tailored for the micro and nanoscale, with emphasis on biological systems. We work at size scales ranging from single molecules to single cells. Applications of this research range from personalized medicine to environmental monitoring. We also have expertise in electrochemistry and fabrication of integrated microfluidic systems.


  • BS (Chemical Engineering) University of Illinois at Urbana-Champaign, 2003
  • MS (Mechanical Engineering) University of Illinois at Urbana-Champaign, 2005
  • PhD (Bioengineering) University of Illinois at Urbana-Champaign, 2007
  • N.S.F. Postdoctoral Fellow Delft University of Technology, NL, 2008-2010

Research & Scholarship Interests

Detection of biomolecules at the nanoscale, specifically inside micro and nanofluidic channels. This is applied to a broad range of scientific fields including: biophysics, micro and systems biology, ecology, environmental sensing, and analytical instrumentation
Affiliated With

Department Research Areas

College Research Initiatives

Honors & Awards

  • 2017 Outstanding Translational Research Award

Selected Publications

  • H.J. Sismaet, A.J. Pinto, E.D. Goluch, Electrochemical Sensors for Identifying Pyocyanin Production in Clinical Pseudomonas Aeruginosa Isolates, Biosensors and Bioelectronics, 97, 2017, 65–69
  • H.J. Sismaet, A. Banerjee, S. McNish, Y. Choi, M. Torralba, S. Lucas, A. Chan, V.K. Shanmugam, E.D. Goluch, Electrochemical Detection of Pseudomonas in Wound Exudate Samples from Patients with Chronic Wounds, Wound Repair and Regeneration, 24(2), 2016, 366-372 *featured in a George Washington University press release
  • T.A. Webster, H.J. Sismaet, I.J. Chan, E.D. Goluch, Electrochemically Monitoring the Antibiotic Susceptibility of Pseudomonas aeruginosa Biofilms, Analyst, 140, 2015, 7195-7201
  • P.N. Abadian, N. Yildirim, A.Z. Gu, E.D. Goluch, SPRi-Based Adenovirus Detection using a Surrogate Antibody Method, Biosensors and Bioelectronics, 74, 2015, 808-814
  • K. Mathwig, T. Albrecht, E.D. Goluch, L. Rassaei, Challenges of Biomarker Detection at the Nanoscale: Nanopores and Microelectrodes, Analytical Chemistry, 87, 2015, 5470-5475
  • T.A. Webster, H.J. Sismaet, A.F. Sattler, E.D. Goluch, Improved Monitoring of P. aeruginosa on Agar Plates, Analytical Methods, 7, 2015, 7150-7155 *emerging investigator themed issue
  • G.E. Aninwene II, P.N. Abadian, V. Ravi, E.N. Taylor, D.M. Hall, A. Mei, G.D. Jay, E.D. Goluch, T.J. Webster, Lubricin: A Novel Means to Decrease Bacterial Adhesion and Proliferation, Journal of Biomedical Materials Research, Part A, 103, 2015, 451-462
  • P.N. Abadian, E.D. Goluch, Using Surface Plasmon Resonance Imaging (SPRi) to Evaluate Bacterial Adhesion on Surface Coatings, Analytical Methods, 7, 2015, 115-122, *featured as a hot article in Analytical Methods
See Google Scholar Profile for all publications »

Related News

September 21, 2018

Research Scientist at the Wyss Institute and current ChE graduate student Daniel Wiegand's research was featured in the ACS Synthetic Biology article "Establishing a Cell-Free Vibrio natriegens Expression System" for using super fold GFP as a read-out for tweaking a multitude of parameters in order to retain sustained protein expression in the cell-free reaction over a long period of time.

November 1, 2017

ChE Associate Professor Ed Goluch was featured in the Northeastern Magazine's article "Faster, Cheaper, Better" for taking an idea of an early infection detection system and bringing it...

October 24, 2017

ChE Associate Professor Ed Goluch gave a talk at the Third Annual Single Cell Analysis USA Congress in Boston on "Isolating Bacterial Cells and Measuring Metabolites Using Sub-Microfluidic Systems," which discusses the unique challenges of bacterial cell analysis at the single cell level given their small size and motility.

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